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Transcription-coupled structural dynamics of topologically associating domains regulate replication origin efficiency

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Abstract Background Metazoan cells only utilize a small subset of the potential DNA replication origins to duplicate the whole genome in each cell cycle. Origin choice is linked to cell growth. differentiation. and replication stress. https://www.roneverhart.com/Western-Digital-Ultrastar-DC-HC570-WUH722222ALE6L4-0F48155-22TB-7-2K-RPM-SATA-6Gb-s-512e-SE-3-5in-Refurbished-HDD/
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